A method of transmitting a reference signal from a base station to a user equipment in a wireless communication system and apparatus therefor are disclosed. The present invention includes dividing a system band into at least one or more partial bands, configuring a time-axis high density reference signal on a high frequency partial band with reference to a center frequency of the system band, configuring a time-axis low density reference signal on a low frequency partial band with reference to the center frequency, and transmitting the configured reference signals to the user equipment.