A vial access device includes a housing having first and second connectors, with the first connector configured to be secured to a first container and the second connector configured to be secured to a second container. The device also includes a spike member extending from the housing and having a proximal end and a distal end. The spike member defines a vent lumen and a fluid lumen spaced from the vent lumen, with each of the vent lumen and the fluid lumen having a distal opening. The distal openings of the vent lumen and the fluid lumen are each defined by a top edge and a bottom edge spaced axially from the top edge. The bottom edge of the fluid lumen is positioned above the distal opening of the vent lumen in a direction extending along a longitudinal axis of the spike member.