The present invention relates to a composition comprising a) Streptomyces microflavus strain NRRL B 50550 and/or a mutant thereof having all the identifying characteristics of the respective strain and/or at least one metabolite produced by the respective strain that exhibits activity against insects mites nematodes and/or phytopathogens and/or a mutant thereof having all the identifying characteristics of the respective strain and/or at least one metabolite produced by the respective strain that exhibits activity against insects mites nematodes and/or phytopathogens and b) at least one further biological control agent selected from specific microorganisms and/or a mutant of it having all identifying characteristics of the respective strain and/or at least one metabolite produced by the respective strain that exhibits activity against insects mites nematodes and/or phytopathogens in a synergistically effective amount. Furthermore the present invention relates to the use of this composition as well as a method for reducing overall damage of plants and plant parts.
