QUINONE-MÉTHIDE PRÉCURSEURS AVEC CHROMOPHORE BODIPY, PROCEDE DE PREPARATION, ACTIVITE BIOLOGIQUE ET APPLICATION EN MARQUAGE FLUORESCENT

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专利权人:

Rudjer Boskovic Institute

发明人:

申请号：

EP16169771.9

公开号：

EP3246331A1

申请日:

2016.05.16

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

The invention relates to BODIPY derivatives of Formula (I):that bear one or more functional groups which in the photochemical reaction upon irradiation with visible light undergo deamination and deliver quinone methides. Furthermore, the invention relates to the antiproliferative activity of BODIPY derivatives and their use for pharmaceutical applications and for fluorescent labeling, particularly for labeling proteins.

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