Paulo J.C. Lin,Yuen Yi c. Tam,Srinivasulu Masuna,Marco A. Ciufolini,Michel Roberge,Pieter R. Cullis
申请号：
US13497395
公开号：
US20120264810A1
申请日:
2010.09.22
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Compositions, methods and compounds useful for enhancing the uptake of a lipid particle b\ a cell are described In particular embodiments, the methods of the invention include contacting a cell with a lipid particle and a compound that binds a Na+/K+ ATPase to enhance uptake of the lipid particle b\ the cell Related compositions useful in practicing methods include lipid particles comprising a conjugated compound that enhances uptake of the lipid particles b\ the cell The methods and compositions are useful in delivering a therapeutic agent to a cell, e g for the treatment of a disease or disorder in a subject
