Leonard, Thomas W.,Coughlan, David C.,Cullen, Alan
申请号：
AU2011341637
公开号：
AU2011341637A1
申请日:
2011.09.23
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
The present invention provides pharmaceutical compositions for oral administration comprising a therapeutically effective amount of a selective factor Xa inhibitor or a pharmaceutically acceptable salt thereof and an enhancer, wherein the enhancer is a medium chain fatty acid or a salt, ester, ether, or derivative of a medium chain fatty acid and has a carbon chain length of from 4 to 20 carbon atoms. The present invention also provides a method for obtaining a reproducible bioavailability of selective factor Xa inhibitor in a subject after oral administration comprising orally administering a pharmaceutical composition as described above.
