According to examples, an apparatus may include a processor and a memory on which is stored machine readable instructions executable by the processor to access test parameters of a patient; calculate average values for each of the accessed test parameters having a reference value range and assign binary coefficient values to the accessed test parameters based on comparison of the average value to the range limits; assign binary coefficient values to the accessed test parameters that do not have the reference value range based on a test parameter presence; generate a patient parameter matrix based on the assigned binary coefficient values; and apply statistical processing to the patient parameter matrix to make a diagnosis.