INHIBITEURS D'HEPARANASE A BASE DE DERIVES DE GLYCOSAMINOGLYCANES PARTIELLEMENT DESULFATES CAPABLES D'ACTIVITE ANTI-ANGIOGENE ET DEPOURVU D'EFFET ANTICOAGULANT

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专利权人:

SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE; S.P.A.

发明人:

CASU, BENITO,TORRI, GIANGIACOMO,NAGGI, ANNAMARIA,GIANNINI, GIUSEPPE,PISANO, CLAUDIO,PENCO, SERGIO

申请号：

CA2457719

公开号：

CA2457719C

申请日:

2001.09.12

申请国别(地区):

CA

年份:

2012

代理人:

摘要：

Partially desulphated glycosaminoglycan derivatives are described,particularly heparin, and more particularly formula (I) compounds where the U,R and R1 groups have the meanings indicated in the description. Saidglycosaminoglycan derivatives are endowed with antiangiogenic and heparanase-inhibiting acitivity ans are devoid of anticoagulant activity.

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