The present invention provides devices and system useful for transporting infants, minimizing vibrations, noise, and associated with transport. Devices of the invention include a head gear assembly, one or more body support rolls for elevating portions of the infant's body, and a mattress system with a removable insert. The invention further provides methods of use associated with such devices, including methods of stabilizing a position of an infant, reducing shock or vibration to an infant during transportation, reducing shock, vibration, or noise exposure to an infant during transportation, reducing shock or vibration while providing elevation to specific portions of an infant during transportation, and reducing the risk of intraventricular hemorrhage and/or persistent pulmonary hypertension to an infant during transportation.