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PRODRUGS OF NMDA RECEPTOR LIGANDS, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR PREPARATION OF PHARMACEUTICAL COMPOSITIONS
专利权人:
BRISTOL-MYERS SQUIBB COMPANY
发明人:
JOHN D. DIMARCO,JACK Z. GOUGOUTAS,IMRE M. VITEZ,MARTHA DAVIDOVICH,MICHAEL GALELLA,TIMOTHY M. MALLOY,ZHENRONG GUO,DENIS FAVREAU
申请号:
IS6714
公开号:
IS2845B
申请日:
2003.02.11
申请国别(地区):
IS
年份:
2013
代理人:
摘要:
There are provided in accordance with the present invention two crystalline polymorphs, designated Form A and Form B, respectively, as well as mixtures thereof, of an epothilone analog represented by the formula Also provided are methods of forming the novel polymorphs, therapeutic methods utilizing them and pharmaceutical dosage forms containing them.
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