Pharmaceutical composition for termination of acute attack of arrhythmia, recovery of sinus rhythm, prevention of recurrence of arrhythmia and / or maintenance of normal sinus rhythm in mammals
Disclosed are pharmaceutical compositions for and methods of preventing or treating acute and/or chronic cardiac arrhythmias in a mammal, including terminating acute episodes of cardiac arrhythmia, restoring normal sinus rhythm, preventing recurrence of cardiac arrhythmia and/or maintaining normal sinus rhythm, which contain a combination of 1-[2-[(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine.1-[2-[(4-フルオロフェニル)メトキシ]エチル]-4-(3-フェニルプロピル)ピペラジンと、1-[2-[ビス(4-フルオロフェニル)メトキシ]エチル]-4-(3-フェニルプロピル)ピペラジンとの組み合わせを含有する、不整脈の急性発作の終結、正常洞調律の回復、不整脈の再発予防及び/又は正常洞調律の維持を含む、哺乳動物における急性及び/又は慢性不整脈の予防又は治療のための医薬組成物及び方法を開示する。