B. DEVADAS,J. WALKER,S. R. SELNESS,T. L. BOEHM,R. C. DURLEY,R. DEVRAJ,B. S. HICKORY,P. V. RUCKER,K. D. JEROME,H. M. MADSEN,E. ALVIRA,M. A. PROMO,R. M. BLEVIS-BAL,L. D. MARRUFO,J. HITCHCOCK,T. OWEN,WIN
申请号：
HK09111945.4
公开号：
HK1135382B
申请日:
2009.12.18
申请国别(地区):
HK
年份:
2012
代理人:
摘要：
Disclosed are compounds of Formula (I) and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, and R5 are defined herein. These compounds are useful for treating diseases and conditions caused or exacerbated by unregulated p38 MAP Kinase and/or TNF activity. Pharmaceutical compositions containing the compounds, methods of preparing the compounds and methods of treatment using the compounds are also disclosed.
