The present invention provides an activation solution based on helping joint activation, comprising the following weight percentage of ingredients: Chili, 15 to 20 %, ginger, 5 to 10 %, lemon grass, 1 to 2 %, mint, 0.5 to 1 % and ethanol, 67 to 78.5 %. It mixes all the above ingredients (chili, ginger, lemon grass and mint) together and then stir. By extracting the solution resulting from the above stirring movement and adding it to the above ethanol to become mixing liquid, the mixing liquid is sealed up till fermentation to become the above activation solution. Accordingly, the present invention can be applied to skin surface that has arthralgia to make it have warm sensation to relieve sensation of pain. The present invention can be absorbed via skin entering into articular cartilage through pore. With appropriate exercise, it can make synovial fluid of cartilage increase to achieve the effectiveness of helping joint activation.本發明係提供一種基於輔助關節活化之活化液,其包含下列重量百分比之原料:辣椒15~20%、薑5~10%、香茅1~2%、薄荷0.5~1%及乙醇67~78.5%;其中,將所述之辣椒、薑及香茅及薄荷混合後進行搗攪,並取其搗攪後所產生之汁液;將所述汁液加入所述乙醇後形成混合液,並將所述混合液予以密封發酵,藉以形成所述活化液;藉之,本發明係可用以塗佈於關節疼痛之皮膚表面,藉以於皮膚表面產生溫熱感,藉可緩解疼痛感,本發明並可經皮膚吸收而由毛孔進入關節軟骨,配合適當的運動,藉以促進軟骨間之關節液增生,以達致輔助關節活化之功效者。