Jay Schneider,Jenny Hsieh,Douglas Frantz,Steven L. McKnight,Joseph M. Ready
申请号：
US11974479
公开号：
US08193225B2
申请日:
2007.10.12
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to compounds and methods for inducing neuronal differentiation in normal neural stem cells and brain cancer stem cells. The compounds are isoxazole amides and derivatives thereof. The methods may take place in vitro, such as in isolates from the adult mammalian brain, or in vivo. Compounds and methods described herein may find use in the treatment of neurodegenerative and psychiatric diseases, the repair and regeneration of the nervous system, and in treatment of neurologic malignancy.
