DAPHNE GENKWA EXTRACTS, AND PHARMACEUTICAL COMPOSITION CONTAINING FRACTIONS OF THE EXTRACTS OR COMPOUNDS SEPARATED FROM THE EXTRACTS AS ACTIVE INGREDIENTS FOR PREVENTING OR TREATING ATOPIC DERMATITIS
Joo Heon Kim;Jae Sung Song;Hyun Woo Oh;Sei Ryang Oh;Da Jung Ji;Jang Mi Sun;Jae Jong Go;Kyung Seop Ahn;Jae Wha Kim;Ho Bum Kang
发明人:
Jae Wha Kim,Kyung Seop Ahn,Ho Bum Kang,Sei Ryang Oh,Jae Jong Go,Joo Heon Kim,Jang Mi Sun,Jae Sung Song,Hyun Woo Oh,Da Jung Ji
申请号：
US14117737
公开号：
US20140072664A1
申请日:
2012.05.17
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to a pharmaceutical composition for the prevention or treatment of atopy comprising the extract of Daphne genkwa, the fraction thereof, of the compound isolated from the same as an active ingredient. More precisely, the extract of Daphne genkwa, the fraction thereof, or the compound isolated from the same, genekwadapnin or yuanhuacine, of the present invention can increase the secretion of cytokine in Th1 immune cells and suppress atopy in the atopy mouse model, so that the extract of Daphne genkwa, the fraction thereof, or the compound isolated from the same of the present invention can be effectively used for the prevention or treatment of atopy.
