As for said film, we are constituted formation namely the formation where two differs (A) and formation (B), by as for this invention, in regard to porimabeshikuru which possesses the asymmetric single layer membrane, the said two formations the said formation (B) contrast, the formation which possesses the effective tonnage of the parents crocking Characteristic block copolymer which at least possesses one stimulus possible hydrophobic polymer block have each parents crocking Characteristic block copolymer which it possesses, (A) as for said block polymer, responding to exogenism stimulus, are offered by the said copolymer which can take new configuration, condition acquire the explosion of the said single layer membrane. This invention production manner of said beshikuru, offers also the manner which encapsulates the active ingredient in said beshikuru and the manner of the discharge where the said active ingredient is controlled.< Choice figure >It is not本発明は、非対称単層膜を有するポリマーベシクルに関し、該膜は、2つの異なる層、すなわち層(A)及び層(B)、によって構成されており、該2つの層は、該層(B)とは対照的に、少なくとも1つの刺激可能な疎水性ポリマーブロックを有する両親媒性ブロックコポリマーの有効量を有する層(A)を有する各両親媒性ブロックコポリマーを有し、該ブロックポリマーは、外因性刺激に応答して新規立体配置を採ることができる該コポリマーにより提供され、該単層膜の破裂を条件付ける。本発明は、該ベシクルの製造方法、該ベシクル中に活性成分をカプセル化する方法、該活性成分の制御された放出の方法も提供する。【選択図】なし
