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Optically active cyclic alcohol compound and process for producing the same
专利权人:
田辺三菱製薬株式会社
发明人:
岡本 征己,櫻木 明,森 敬和,岸田 宗己,東島 孝典
申请号:
JP2013209007
公开号:
JP5607805B2
申请日:
2013.10.04
申请国别(地区):
JP
年份:
2014
代理人:
摘要:
The present invention relates to a method for preparing an optically active cyclic alcohol compound represented by general formula [I]: [wherein R represents a hydrogen atom or a protecting group for amino group, and * represents an asymmetric carbon atom.] which comprises a step of subjecting a cyclic ketone compound represented by general formula [II]: [wherein R has the same meaning as defined above.] to asymmetric reduction (A) in the presence of an optically active oxazaborolidine compound and a boron hydride compound, or (B) in the presence of an asymmetric transition metal complex obtained from a transition metal compound and an asymmetric ligand and a hydrogen donor, and relates to said compound.
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