A device for platelet production, a platelet manufacturing apparatus and a platelet manufacturing method for efficiently and stably producing platelets using megakaryocytes are provided. A device for manufacturing platelets used for producing platelets from megakaryocytes, wherein the device for platelet production comprises at least a first member and a flow path depth adjusting member, the first member comprises a second member A megakaryocyte can be held by combining, a liquid for applying a shearing force can be flowed to the megakaryocyte, a flow path including an outlet of the manufactured platelets is formed, and the flow path When the first member is combined with the second member, the depth adjusting member is arranged such that one end side of the flow path has a depth allowing passage of the megakaryocyte and a flow of the platelet at the other end side of the flow path The problem can be solved by a device for platelet production which adjusts the depth of the flow path so that the outlet is shallower in the depth of the flow path.巨核球を用いて血小板を効率よく、且つ安定的に製造するための血小板製造用デバイス、血小板製造装置及び血小板製造方法を提供する。 巨核球から血小板を製造するために用いられる血小板製造用デバイスであって、前記血小板製造用デバイスは、第1部材及び流路深さ調整部材を少なくとも含み、前記第1部材は、第2部材と組み合すことで巨核球を保持することができ、前記巨核球にせん断力を付与するための液体を流すことができ、且つ製造した血小板の流出口を含む流路を形成し、前記流路深さ調整部材は、前記第1部材を前記第2部材と組み合わせた際に、前記流路の一端側は前記巨核球が通過できる深さで、且つ前記流路の他端側の血小板の流出口の方が流路の深さが浅くなるように流路の深さを調整する、血小板製造用デバイスにより、課題が解決できる。
