MARTINI, PAOLO G.V. PGV,NATARAJAN, MADHUSUDAN M,HASLETT, PATRICK ANTHONY JOHN PAJ,SEYMOUR, ALBERT BARNES AB,‧馬丁尼,‧納塔拉詹,‧哈斯利特,‧西摩
申请号：
HK15109600.6
公开号：
HK1208819A
申请日:
2015.09.30
申请国别(地区):
HK
年份:
2016
代理人:
摘要：
The present invention provides, among other things, improved anti-CCL2 antibodies characterized with high affinity, potency, tissue selectivity and/or epitope specificity, and uses thereof, in particular, for treatment of scleroderma and related fibrotic and/or inflammatory diseases, disorders and conditions. In some embodiments, the present invention provides methods and compositions for treatment of scleroderma and related fibrotic and/or inflammatory diseases, disorders and conditions based on an anti-CCL2 antibody having an affinity of 10&minus；12 M or greater.
