Philippe G. Nantermet;Constantine Kreatsoulas;Zhi-Qiang Yang;Hong Zhu;Abbas M. Walji
发明人:
Philippe G. Nantermet,Zhi-Qiang Yang,Constantine Kreatsoulas,Abbas M. Walji,Hong Zhu
申请号:
US13635286
公开号:
US20130012526A1
申请日:
2011.04.18
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention is directed to certain Oxazole derivatives which are useful as modulators of Fatty Acid Amide Hydrolase (FAAH) and as FAAH imaging agents. The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including osteoarthritis, rheumatoid arthritis, diabetic neuropathy, postherpetic neuralgia, skeletomuscular pain, and fibromyalgia, as well as acute pain, migraine, sleep disorder, Alzheimer Disease, and Parkinson's Disease.