Bart Barlogie;John D. Shaughnessy, JR.;John D. Shaughnessy; JR.
发明人:
John D. Shaughnessy, JR.,Bart Barlogie
申请号：
US13501933
公开号：
US20120269802A1
申请日:
2010.10.13
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention provides a method treating a myeloma patient by administering one or more of thalidomide, a Total Therapy 2 regimen, an interleukin-6 signaling suppressor, an interleukin-6R signaling suppressor, an IGF1 signaling suppressor, an IGF1 R signaling suppressor, shRNA or other modulators of gene expression. Also, provided are methods for predicting outcome of a treatment for an individual having a cancer, e.g., myeloma, by performing one or more of karyotyping or expression profiling of chromosomes 1 and 13 or expression level measurement of IL-6R.
