CAREBAY HOLDING LTD., COMPANY NO. 681498;ITERO BIOPHARMACEUTICALS, INC.
发明人:
LAWLIS, V. BRYAN,HAYENGA, KIRK J.,HORTON, DARLENE P.,GIAMBATTISTA, LUCIO,DESALVO, DAVID,BENDEK, ANTONIO
申请号：
ES11801536
公开号：
ES2533312T3
申请日:
2011.07.05
申请国别(地区):
ES
年份:
2015
代理人:
摘要：
A single-use device (100, 1000, 100) for the self-release of the follicle stimulating hormone solution. The device includes: an elongated main housing (110, 1010, 1110)； a rotary rotator (118)； a knob (160, 1015, 1115)； a piston rod (116)； a needle assembly (140)； and a cartridge holder (150) the elongate main housing has distal (111) and proximal portions (112) disposed along the longitudinal axis； with the characteristic that the rotating rotator is connected to the proximal portion of the main and rotating housing on the longitudinal axis with respect to the main housing； the knob extends from the proximal portion and is rotatable with respect to the main housing between a blocking position and seven or less discrete dosing positions to adjust the release of variable dose of the follicle stimulating hormone (FSH) solution, the knob has longitudinally spaced elements (908) corresponding respectively to the closed position and to the seven or less discrete dosing positions； the piston rod is rotatably coupled to a portion of the rotator and is oriented by a longitudinally spring, the piston rod is rotatably locked to the knob in the locked position in the element corresponding to the locked position, the The piston rod is movable incrementally along the longitudinal axis between the element corresponding to the blocking position and one of the elements of the seven or less discrete dosing positions； the needle assembly is permanently enclosed with a permanently attached needle, which has an inner end (425) and a working end (424)； the cartridge holder is proximally attached to the needle assembly, the cartridge holder holds an elongated drug cartridge (130) containing the FSH solution, this solution is sterile and free of preservatives to allow only a single use of the device, The drug cartridge is permanently enclosed within the cartridge holder and with a penetrable membrane (133) adjacent to the inner end of the needle and the mobile plunger (131, 132) adjacent
