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PHARMACEUTICAL COMPOSITIONS OF CLEVIDIPIN AND METHODS OF PREPARING CONCENTRATIONS THEREOF
专利权人:
HOSPIRA, INC.;HOSPIRA; INC.;THE MEDICINES COMPANY
发明人:
RAMAKRISHNA KORNEPATI,FLOOD KEITH,MOTHERAM, RAJESHWAR,KRISHNA, GOPAL,DING, MIN
申请号:
DK09803550
公开号:
DK2320740T3
申请日:
2009.07.29
申请国别(地区):
DK
年份:
2014
代理人:
摘要:
A pharmaceutical composition is provided which comprises clevidipine as an active ingredient and has a level of the degradants Substance 23, Substance 24 and Substance 25 that is approximately equal to or no more than 0.2% on a weight-by-weight of impurity basis to clevidipine and an amount of the impurity H168/79 that is no greater than about 1.5%.
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