A bottle holder for a syringe includes a stop surface, a piercing hollow spike protruding beyond the stop surface, a guideway, and a first and a second clamping element. Each clamping element includes a through-hole and is moveable back and forth between an insertion position and a clamping position. When the clamping elements are in the insertion position, a neck of the bottle can be moved through the through-holes until the front end of the bottle abuts against the stop surface such that the piercing hollow spike pierces a film at the front end of the bottle. At least one of the clamping elements in its clamping position presses against the neck of the bottle in order to clamp the bottle in the holder.
