SUN, HAIZHOU,XU, XIAOMING,ZHOU, MING,HARRAN, SUSAN,HANSON, GUNNAR, JAMES
申请号:
EP10830467
公开号:
EP2493879A4
申请日:
2010.10.28
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The invention provides small molecule mimics (IV) of the Smac peptide that are dimers or dimer-like compounds having two binding domains connected by a linker. These compounds are useful to promote apoptosis. The invention includes pharmaceutical compositions comprising such compounds and methods to use them to treat conditions including cancer and autoimmune disorders.