HOWARD, Steven,LI, Yue,LU, Yipin,MORTENSON, Paul,SMITH, Troy,SUNG, Moo,WOODHEAD, Steven,WRONA, Wojciech,BESONG, Gilbert,BRAIN, Christopher Thomas,BROOKS, Clinton A.,CONGREVE, Miles Stuart,DAGOSTIN, Cl
申请号：
MEP2511
公开号：
ME01282B
申请日:
2009.08.20
申请国别(地区):
ME
年份:
2013
代理人:
摘要：
Disclosed compound is related to treatment and therapy illness relevant to kinases for albumen. Also needing compound can be used to treat or prevent or improve one or more symptom cancers, transplant rejection and autoimmune disease. In addition, it is necessary to method adjust kinases activity, such as CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK9 CDK8 and using the compound it is as described herein.Prikazana jedinjenja se odnose na lečenja i terapije poremećaja povezanih sa protein kinazom. Takođe postoji potreba za jedinjenj ima koja se mogu koristiti za lečenje ili prevenciju ili poboljšanje jednog ili više simptoma kancera, odbacivanja transplanta, i autoimunih bolesti. Osim toga, postoji potreba za metodama za moduliranje aktivnosti protein kinaza, kao što su CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8 i CDK9, primenom jedinjenja koja su ovde data.
