The present disclosure relates to systems and methods for positioning an X-ray scanner. The systems may perform the methods to obtain one or more images relating to the target in the object； determine one or more image target locations corresponding to the target based on the one or more images； determine a target position of the target based on the one or more image target locations corresponding to the target； and determine positioning information of an indicator or an X-ray source of the X-ray scanner based on the target position.
