John J. Baldwin,Salvacion Cacatian,David A. Claremon,Lawrence W. Dillard,Patrick T. Flaherty,Alexey V. Ishchenko,Lanqi Jia,Gerard McGeehan,Robert D. Simpson,Suresh B. Singh,Colin M. Tice,Zhenrong Xu,J
申请号:
US12665219
公开号:
US08106221B2
申请日:
2008.06.20
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is directed to aspartic protease inhibitors. The present invention is also directed to pharmaceutical compositions comprising the disclosed aspartic protease inhibitors. The present invention is further directed to methods of antagonizing one or more aspartic proteases in a subject in need thereof, and methods for treating an aspartic protease mediated disorder in a subject using the disclosed aspartic protease inhibitors.