Substituted pyrazoles as heat shock transcription factor activators

• 收藏
• 分享

专利权人:

Dennis J Thiele;Daniel W Neef;Jose S Mendoza

发明人:

Dennis J Thiele,Daniel W Neef,Jose S Mendoza

申请号：

US12945522

公开号：

US09315449B2

申请日:

2010.11.12

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The present invention relates to substituted pyrazole compounds, methods for their discovery, and their research and therapeutic uses, and pharmaceutical Formulations thereof. In particular, the present invention provides substituted pyrazole compounds capable of facilitating HSF1 homotrimerization, and methods of using such compounds as therapeutic agents to treat a number of conditions associated with irregular HSF1 activity.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/