The present invention is a composition for transdermal delivery of a therapeutic agent and methods of treating a medical condition utilizing the composition. The composition comprises a natural oil, or first oil, of about 40% to about 75% w/w of the composition and contains about 3% to 11% behenic acid, a second oil of about 2% to about 15% w/w of the composition and contains oleic and/or palmitic acids selected from the group consisting of Tamanu oil, Argan oil, Shea butter, Pecan oil, canola oil, olive oil, poppy seed oil, sesame oil, sea buckthorn oil, grape seed oil, sunflower oil, macadamia oil, hemp oil, soybean oil, pumpkin seed oil, Borneo tallow nut oil, maracuja oil, marula oil, neem oil, baobab oil, rosehip oil, and cocoa butter and an emulsifying wax of about 9% to about 32% w/w of the composition.