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1,3,4-oxadiazole sulfonamide derivative compounds as histone deacetylase 6 inhibitor, and the pharmaceutical composition comprising the same
专利权人:
Chong Kun Dang Pharmaceutical Corp.
发明人:
Jaekwang Lee,Younghue Han,Yuntae Kim,Daekyu Choi,Jaeki Min,Miseon Bae,Hyunmo Yang,Dohoon Kim
申请号:
US15747952
公开号:
US10538498B2
申请日:
2016.07.27
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to novel compounds represented by the formula I having histone deacetylase 6 (HDAC6) inhibitory activity, stereoisomers thereof or pharmaceutically acceptable salts thereof, the use thereof for the preparation of therapeutic medicaments, pharmaceutical compositions containing the same, a method for treating diseases using the composition, and methods for preparing the novel compounds. (I) The novel compounds, stereoisomers thereof or pharmaceutically acceptable salts thereof according to the present invention have histone deacetylase (HDAC) inhibitory activity and are effective for the prevention or treatment of HDAC6-mediated diseases.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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