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Methods and compositions for maintaining the conformation and structural integrity of biomolecules
专利权人:
TissueGen; Inc.
发明人:
Kevin D. Nelson,Brent B. Crow,Nickolas B. Griffin,Jennifer Seifert,Paul R. Sood,Alpeshkumar P. Patel,Paul A. Hubbard
申请号:
US15653414
公开号:
US10363281B2
申请日:
2017.07.18
申请国别(地区):
US
年份:
2019
代理人:
摘要:
A composition includes a target pharmaceutical or biological agent, a solution containing the target pharmaceutical or biological agent, and substrate that is soluble in the solution. The substrate is capable of being solidified via a solidification process and the solidification process causes the substrate to become physically or chemically cross-linked, vitrified, or crystallized. As a result of the solidification process, particles are formed. The target pharmaceutical or biological agent within the solution retains proper conformation to ultimately produce a desired effect.
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