Example methods and systems for generating an aggregated artificial intelligence (AI) engine for radiotherapy treatment planning are provided. One example method may include obtaining multiple AI engines associated with respective multiple treatment planners； generating multiple sets of output data using the multiple AI engines associated with the respective multiple treatment planners: comparing the multiple AI engines associated with the respective multiple treatment planners based on the multiple sets of output data； and based on the comparison, aggregating at least some of the multiple AI engines to generate the aggregated AI engine for performing the particular treatment planning step. The multiple AI engines may be trained to perform a particular treatment planning step, and each of the multiple AI engines is trained to emulate one of the multiple treatment planners performing the particular treatment planning step.
