KUCERA, DAVID,HALEY, GREGORY J.,RUEDEN, ERIK J.,WANG, TINGMAN,VIERTELHAUS, MARTIN,BLATTER, FRITZ
申请号：
PL07873546
公开号：
PL2076132T3
申请日:
2007.10.16
申请国别(地区):
PL
年份:
2013
代理人:
摘要：
The present disclosure relates to p-toluene sulfonic acid salt of 5-amino-3-(2&prime；-O-acetyl-3&prime；-deoxy-beta-D-ribofuranosyl)-3H-thiazolo[4,5-d]pyrimidin-2-one and to its use in treating conditions such as viral infections, tumors, and cancer. Also disclosed is a method of preparing the p-toluene sulfonic acid salt of 5-amino-3-(2&prime；-O-acetyl-3&prime；-deoxy-&bgr；-D-ribofuranosyl)-3H-thiazolo[4,5-d]pyrimidin-2-one and methods for producing furanose compounds which are useful intermediates in the preparation of pharmaceutical compounds such as p-toluene sulfonic acid salt of 5-amino-3-(2&prime；-O-acetyl-3&prime；-deoxy-&bgr；-D-ribofuranosyl)-3H-thiazolo[4,5-d]pyrimidin-2-one and the like.
