KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY;KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
发明人:
Sungchan Cho,Miri Choi,Joo Youn Lee
申请号：
US16470014
公开号：
US10765669B2
申请日:
2017.12.15
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to a pharmaceutical composition the prevention or treatment of DYRK-related diseases containing a pyridine-based compound as an active ingredient, a pyridine-based compound of the present invention which is used as an active ingredient of the pharmaceutical composition inhibits the activity of DYRK1A with very high efficacy and selectivity, thereby can be used effectively in the prevention or treatment of DYRK-related diseases, such as Down syndrome, degenerative brain diseases, cancer, and metabolic diseases.
