Immediate release, oral, pharmaceutical formulation comprising nalbuphine or a pharmaceutically acceptable salt thereof, and at least one hydrophilic granulation carrier, one hydrophilic binder and one lubricant.本發明關於一種立即釋放之口服藥學調配物,其包含納布啡(nalbuphine)或其藥學上可接受之鹽及至少一種親水性粒化載劑、一種親水性黏合劑和一種潤滑劑。