It is intended to provide a novel structure comprising collagen and a materialfor tissue regeneration containing the same both of which improve the promotionof nerve tissue regeneration, the healing/regeneration of the lost part of body'ssoft tissue or the like without a combination with laminin or a nerve growth factor(NGF). The structure comprising collagen according to the invention has a thinfilm multilocular structure and is different from a colloidal state, a gelledstate and a fibrous state. Therefore, when the novel structure comprising collagenaccording to the invention is used for the material for tissue regeneration,amazingly, the promotion of regeneration of body tissue such as nerve tissue,hypodermal tissue, submucosal tissue, biological membrane tissue, adiposetissue, muscular tissue, dermal tissue, or gingival tissue, the shorteningof healing period, functional recovery or the like can be improved. Further,when it is applied to a patient having neuropathic pain, the pain can be taken away.