Disclosed is a pharmaceutical composition for preventing or treating hearing loss, comprising Cuscuta japonica Choisy extract, or the extract of Rehmannia glutinosa Libschitz var. purpurea MAKINO and Cuscuta japonica Choisy. In addition, the present invention provides a food composition for preventing or ameliorating hearing loss, comprising Cuscuta japonica Choisy extract, or the extract of Rehmannia glutinosa Libschitz var. purpurea MAKINO and Cuscuta japonica Choisy. The composition inhibits hearing loss, in particular, acoustic trauma, temporary or permanent hearing loss by effectively inhibiting the threshold shift induced by noise and the likes, and thusit is effective in preventing or treating hearing loss. In addition, it can be administered orally, thereby drug compliance of patients can be enhanced.
