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COMPOSITION PHARMACEUTIQUE CONTENANT UN COMPOSE ACTIF SUR LE PLAN OPTIQUE POSSEDANT UNE ACTIVITE D'AGONISTE DU RECEPTEUR DE LA THROMBOPOIETINE ET SON INTERMEDIAIRE
专利权人:
LTD.;SHIONOGI & CO.
发明人:
TAKAYAMA, MASAMI,KUROSE, NORIYUKI
申请号:
CA2694567
公开号:
CA2694567C
申请日:
2008.07.29
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
An optically active 4-phenylthiazole derivative having a thrombopoietinreceptoragonist activity and a pharmaceutical composition containing the presentcompoundas an active ingredient are created, and a platelet production regulatingagent whichcan be orally administered is provided.Disclosed is a pharmaceutical composition containing, as an active ingredient,an optically active compound represented by the formula:(see above formula)wherein, R1 is a halogen atom or C1-C3 alkyloxy; R2 is C1-C8 alkyl; R3 is C1-C8 alkyl;R4 and R5 are each independently a fluorine atom or chlorine atom; R6 is C1-C3alkylor C1-C3 alkyloxy; * indicates that a carbon atom marked with an asterisk isanasymmetric carbon, a pharmaceutically acceptable salt thereof, or a solvatethereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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