Albino Manuel PEREIRA MARTINS,Ana Catarina FREITAS SALAZAR DE OLIVEIRA,Rui Luís GONÇALVES DOS REIS,Nuno João MELEIRO ALVES DAS NEVES
申请号:
US15307698
公开号:
US20170051050A1
申请日:
2015.04.28
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to biofunctional polymeric substrates product comprising immobilized antibodies that selective bind to antigens namely autologous growth factors and an inflammatory molecule, uses and method of production. The bio-functional polymeric substrate can be used in a quantification method of antigens namely soluble growth factors, inflammatory molecules and hormones or the biofunctional polymeric substrate can be used to isolate extracellular vesicules. The biofunctional polymeric substrate can be also used in Tissue Engineering and Regenerative Medicine approaches, namely in bone and cartilage lesions, esophageal lesions, periodontal ligament reconstruction and skin lesions regeneration or treatment.