A blood pressure cuff may comprise an alignment component, a sleeve, and a tapered inflatable bladder disposed within the sleeve. The tapered inflatable bladder may have a width that increases as the distance from the alignment component increases, and the tapered inflatable bladder and the alignment component may be configured to position the blood pressure cuff around a limb having a blood vessel and a circumference, such that at a position coincident with the blood vessel, the width of the tapered inflatable bladder is about 40% of the circumference of the limb. A method of using such a blood pressure cuff may comprise placing the alignment component at the position coincident with the blood vessel of the limb, wrapping the cuff around the limb such that the width of the tapered inflatable bladder overlaying the blood vessel is about 40% of the circumference of the limb, and inflating the bladder.
