IMMUNOLOGICAL PROCESS FOR DETECTING ANTIBODIES DIRECTED TOWARDS TISSUE TRANSGLUTAMINASE (TTG), USE OF TTG FOR DIAGNOSTIC PURPOSES AND THERAPY CONTROL, AND ORAL PHARMACEUTICAL AGENT CONTAINING TTG
EHNIS, TOBIAS,SCHUPPAN, DETLEF,DIETERICH, WALBURGA DR
申请号:
HU0202779
公开号:
HU228479B1
申请日:
1997.07.14
申请国别(地区):
HU
年份:
2013
代理人:
摘要:
The invention relates to a method for detecting antibodies from body fluids by means of an immune reaction with tissue transglutaminase (tTG), with tTG-containing compounds, the antigenic structures, immunoreactive sequences or analogues thereof. The method may be used in the diagnosis and therapy control of diseases associated with an immune reaction against tTG, tTG-containing compounds, the antigenic structures, immunoreactive sequences or analogues thereof. Therefore, the invention is also directed to the use of tTG and the above-mentioned substances in diagnosis and therapy control, preferably in the diagnosis and therapy control of chronically inflammatory diseases or autoimmune diseases, and more preferably, in the diagnosis and therapy control of sprue or coeliac disease.