Dave, Vipul,Falotico, Robert,Li, Chengxue,Nguyen, Thai M.,Parker, Theodore L.,Zhao, Jonathon Z.
申请号：
AU2009240874
公开号：
AU2009240874B2
申请日:
2009.11.27
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
#$%^&*AU2009240874B220151126.pdf#####- 43 Abstract 5 An expandable medical device includes a plurality of elongated struts, forming a substantially cylindrical device which is expandable from a first diameter to a second diameter. A plurality of different beneficial agents may be loaded into different openings within the struts for delivery to the tissue. For treatment of conditions such as restenosis, different agents are loaded into different openings in 10 the device to address different biological processes involved in restenosis and are delivered at different release kinetics matched to the biological process treated. The different agents may also be used to address different diseases from the same drug delivery device. In addition, anti-thrombotic agents may be affixed to at least a portion of the surfaces of the medical device for the prevention of sub-acute 15 thrombosis. To ensure that the different agents remain affixed to the device as well as to each other, primer layers may be utilized. 20 23/I I/09.va 18382 speci.doc,431/7 10 12 14 FIG 20 2 12 000 22 0 0 30 0 30 000 0 0b FIG. 1 200 230 @0 O 0 230o 230 FIG. 2
