IN VITRO METHOD FOR MODIFYING THE DEPLETION PROFILE OF TREG CELLS PRESENT IN A TOTAL SPLENOCYTE POPULATION OF A BIOLOGICAL SAMPLE BY MEANS OF THE ISOLATION, CULTURING AND EXPOSURE THEREOF TO AN ATP AND POLYMIXIN B MEDIUM

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专利权人:

发明人:

Claudio Acuna,Claudio Capelli,Claudio Coddou,Alejandro Escobar,Monica Imarai,Yohana Labra,Ximena Lopez,Miguel Rios,Mercedes Lopez

申请号：

US14181810

公开号：

US20140371159A1

申请日:

2014.02.17

申请国别(地区):

US

年份:

2014

代理人:

摘要：

In vitro method to modify the deplexion profile of Treg Cells present in a total splenocyte population of a biological sample comprising isolating, cultivating and submitting the splenocyte at a ATP medium and polymyx B, where the splenocytes at concentrations of Polymyxin B in the range 0.1 μg/ml to 100 μg/ml, and combined use of Polymyxin B and ATP to prepare a medicament useful in the treatment tumor or cancer mammals, where cancer is melamine.

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