Provided are an agent for the treatment and/orprophylaxis of an anxiety disorder, such as panic disorder,agoraphobia, obsessive-compulsive disorder, social phobia,posttraumatic stress disorder, particular phobia, generalizedanxiety disorder or the like, comprising, as an activeingredient, a thiazole derivative represented by the formula(I) wherein R1 represents aryl or the like, and R2 representspyridyl or the like, or a pharmaceutically acceptable saltthereof, and the like.(see formula I)