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Hydrocortisone controlled release formation
专利权人:
DIURNAL LIMITED
发明人:
Huatan Hiep,Ross Richard,Whitaker Martin
申请号:
NZ71561613
公开号:
NZ715616A
申请日:
2013.02.12
申请国别(地区):
NZ
年份:
2017
代理人:
摘要:
The disclosure relates to a pharmaceutical formulation comprising a core comprising hydrocortisone and a carrier and contacting said core a layer comprising a delayed release polymer wherein said delayed release polymer is a pH sensitive enteric polymer and is a mixture of poly (methacrylic acid, methyl methacrylate) in a ratio of 1:1 and poly (methacrylic acid, methyl methacrylate) in a ratio of 1:2 and its use in the treatment of conditions that would benefit from a delayed release of hydrocortisone, in particular conditions such as adrenal insufficiency, inflammatory conditions and depression.
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