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Compositions with Thixotropy and Enhanced Dissolution Reproducibility and Stability
专利权人:
发明人:
Michael S. Zamloot,Roger Fu,Su Il Yum,Wendy Chao,Huey-Ching Su
申请号:
US14776608
公开号:
US20160038479A1
申请日:
2014.03.14
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present disclosure provides extended release compositions including, formulations that comprise such compositions, which exhibit desirable dissolution of an active agent while maintaining its physical stability in a dosage form including, for example, providing reduced sample variability, e.g., in the form of reduced inter-capsule variability and/or a reduction in storage-time dependent change in mean release of the active agent from the composition. Related methods of making and administering the disclosed compositions and formulations are also provided.
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