ROVATI, LUCIO CLAUDIO,NAGELL, ASTRID,XIOL, AGUIRRE JAIME,RULL, PROUS SANTIAGO,POHL, RALF-TORSTEN,MENGS, ULRICH
申请号:
CA2761656
公开号:
CA2761656C
申请日:
2010.05.14
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The invention relates to a method for the preparation of amorphous silibinin(or its synonyms: silybin or silibin)derived from a milk thistle fruit extract having an increased release rate andimproved absorbability or bioavailability, and to theuse of amorphous silibinin for the treatment or prevention of liver diseases,preferably for the treatment of viral hepatitis, e.g.hepatitis B or C, in particular in a patient who will undergo or has undergoneliver transplantation. Preferably, the amorphoussilibinin is adapted for oral administration.