INSERM (Institut National de la Santé et de la Recherche Médicale);Université Nice Sophia Antipolis;Centre National de la Recherche Scientifique (C.N.R.S.)
A compound of general formula (1) ** (See formula) ** wherein Q1 to Q5 identical or different represent CR6 R1 represents a C6-C10 aryl comprising one or two fused rings, wherein from 2 to 5 atoms of Carbon can be replaced with a heteroatom selected from O, S, N and NR6, and eventually substituted with 5 to 11 substituents selected from R6, halo, CN, NO2, CF3, OCF3, COOR6, OCOR6, SO2NR6R7, CONR6R7, NR6R7, NR6COR7, (CH2) p- NR6R7, (CH2) p- OR6 and (CH2) pSR6. R2 is SO2R1 or R6 R3 and R4 identical or different are selected from COR8 and R6 R5 represents R6, aryl, OR6, SR6, halo, CN, NO2, CF3, OCF3, COOR6, SO2NR6R7, CONR6R7, NR6R7 and NHCOR6, R6 and R7 identical or different represent an H or R8 alkyl is selected from H, alkyl, cycloalkyl, aryl, alkylaryl, wherein the aryl can be substituted with one to four identical or different R5 substituents, or R8 represents - (CH2) q-NR6R7 . p represents an integer from 0 to 6, q represents an integer from 0 to 6, where the thiazolyl group is attached to a group of 6 members in the meta position or stops with respect to the sulfonamide group and where the thiazolyl group is bound to a group of 6 members in position α or β with respect to the S atom, with the exclusion of the following compounds: N- [4- [3 - [[(4-chlorophenyl) sulfonyl] amino] phenyl] -2 -thiazolyl] -2-hydroxybenzamide, 2- (acetyloxy) -N- [4- [3 - [[(4-chlorophenyl) sulfonyl] amino] phenyl] -2-thiazolyl] -benzamide, 3-chloro-N- [ 4- [3 - [[(4-chlorophenyl) sulfonyl] amino] phenyl] -2-thiazolyl] -benzamide, N- [4- [3 - [[(4-chlorophenyl) sulfonyl] amino] phenyl] -2- thiazolyl] -1-hydroxy-2-naphthalenecarboxamide, N- [4- [3 - [[(4-chlorophenyl) sulfonyl] amino] phenyl] -2-thiazolyl] -3-hydroxy-2-naphthalenecarboxamide, N- [4 - [3 - [[(4-chlorophenyl) sulfonyl] amino] phenyl] -2-thiazolyl] -2-methoxybenzamide, N- [3- (2-amino-4-thiazolyl) phenyl] -4-chloro-benzenesulfonamide, N- [4- [3 - [[(4-chlorophenyl) sulfonyl] amino] phenyl] -2-ti azolyl benzamide, 2-chloro-N-
