The biopsy system includes an endoscope having an insertion portion having a channel and an active bending portion capable of bending operation, a needle tube having a distal end region and a proximal end region having a higher flexural rigidity than the distal end region, A sheath portion which can be inserted and into which the needle tube is inserted an attachment adapter which is provided on the proximal end side of the sheath portion and is attachable to the endoscope and the distal end region and the proximal end region are connected And a connecting member, wherein, when the connecting member is located on the proximal side of the proximal end of the active bending portion of the insertion portion and the distal end of the inserting portion is located in the duodenal bulb portion It is possible to move only within the range of the distal end side of the proximal end of the scanning curved region passively curable along the stomachs great curvature.生検システムは、チャンネルを有する挿入部と、湾曲操作可能な能動湾曲部とを有する内視鏡と、先端領域及び前記先端領域よりも曲げ剛性の高い基端領域を有する針管と、前記チャンネルに挿入可能であり、前記針管が挿通されるシース部と、前記シース部の基端側に設けられ、前記内視鏡に装着可能な取付アダプタと、前記先端領域と前記基端領域とを接続する接続部材と、を備え、前記接続部材は、前記挿入部のうち、前記能動湾曲部の基端よりも基端側であって、かつ前記挿入部の先端を十二指腸球部に位置させたときに胃の大弯に沿って受動的に湾曲可能な倣い湾曲領域の近位端よりも先端側の範囲内のみを移動可能である。